Pseudovitamin B12 Biosynthesis
نویسندگان
چکیده
منابع مشابه
Illuminating the black box of B12 biosynthesis.
Tetrapyrroles are nearly ubiquitous in nature as participants in a wide variety of biological reactions that are central to life, such as electron transfer, gas binding, and one-carbon metabolism (1, 2). Because of their diverse colors—for example the greens of plant chlorophylls, reds of blood, and blues and browns of avian eggs—tetrapyrroles have been called the “pigments of life.” The chemic...
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It has been reported (l-5) from this laboratory that vitamin Blz functions in vivo and in vitro in the incorporation of amino acids into protein. There was observed a reduction in the incorporation of amino acids into protein in vitamin Brz-deficient pigs and rats in vivo as compared to normal animals (4). Similar reduction in the incorporation of amino acids was observed upon incubation of liv...
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Vitamin B12 (cobalamin) is required by humans and other organisms for diverse metabolic processes, although only a subset of prokaryotes is capable of synthesizing B12 and other cobamide cofactors. The complete aerobic and anaerobic pathways for the de novo biosynthesis of B12 are known, with the exception of the steps leading to the anaerobic biosynthesis of the lower ligand, 5,6-dimethylbenzi...
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Vitamin B12 contents in the edible cyanobacterium Nostoc flagelliforme, also known as hair vegetable, were assayed using a microbiological method. We detected high vitamin B12 contents in samples of naturally grown cells (109.2 ± 18.5 μg/100g dry weight) and cultured cells (120.2 ± 53.6 μg/100g dry weight). However, commercially available hair vegetable samples, which comprised fake substitutes...
متن کاملA Differential Microbiological Assay
Although vitamin B12 can be assayed biologically with mice, chicks or rats, the microbiological method of assay is preferred since it is more rapid and economical. One serious shortcoming of many microbiological B12 assay procedures is the lack of specificity when crude materials are assayed. Crude materials can contain inhibitory or stimulatory factors which cause serious errors in assay resul...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1969
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)91736-9